Involvement of PD-L1 on tumor cells within the escape from host immune system and tumor immunotherapy by PD-L1 blockade.
PD-1 is a receptor of the Ig superfamily that negatively regulates T cell antigen receptor signaling by interacting with the particular ligands (PD-L) and is usually recommended to play a task within the upkeep of self-tolerance. Within the current examine, we examined potential roles of the PD-1/PD-L system in tumor immunity.
Transgenic expression of PD-L1, one of many PD-L, in P815 tumor cells rendered them much less prone to the particular T cell antigen receptor-mediated lysis by cytotoxic T cells in vitro, and markedly enhanced their tumorigenesis and invasiveness in vivo within the syngeneic hosts as in contrast with the parental tumor cells that lacked endogenous PD-L.
Each results might be reversed by anti-PD-L1 Ab. Survey of murine tumor traces revealed that the entire myeloma cell traces examined naturally expressed PD-L1.
Rat Costimulatory molecules B7H4 ELISA equipment |
Development of the myeloma cells in regular syngeneic mice was inhibited considerably albeit transiently by the administration of anti-PD-L1 Ab in vivo and was suppressed fully within the syngeneic PD-1-deficient mice.
These outcomes counsel that the expression of PD-L1 can function a potent mechanism for doubtlessly immunogenic tumors to flee from host immune responses and that blockade of interplay between PD-1 and PD-L might present a promising technique for particular tumor immunotherapy.
B7H4 antibody |
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| MBS837940-01mg | MyBiosource | 0.1mg | EUR 1030 |
B7H4 antibody |
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| MBS837940-5x01mg | MyBiosource | 5x0.1mg | EUR 4490 |
B7H4 antibody |
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| MBS838018-0025mg | MyBiosource | 0.025mg | EUR 425 |
B7H4 antibody |
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| MBS838018-01mg | MyBiosource | 0.1mg | EUR 1040 |
B7H4 antibody |
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| MBS838018-5x01mg | MyBiosource | 5x0.1mg | EUR 4535 |
B7H4 Rabbit mAb |
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| E2R23579 | EnoGene | 100ul | EUR 255 |
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Description: Available in various conjugation types. |
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B7H4 Rabbit mAb |
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| 57227 | SAB | 100ul | EUR 399 |
B7H4 Rabbit mAb |
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| E2R90021 | EnoGene | 100ul | EUR 585 |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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B7H4 antibody (PE) |
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| 61R-1382 | Fitzgerald | 100 tests | EUR 758 |
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Description: Mouse monoclonal B7H4 antibody (PE) |
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B7H4 antibody (PE) |
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| 61R-1389 | Fitzgerald | 100 ug | EUR 300 |
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Description: Rat monoclonal B7H4 antibody (PE) |
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B7H4 antibody (PE) |
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| MBS832770-01mg | MyBiosource | 0.1mg | EUR 1290 |
B7H4 antibody (PE) |
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| MBS832770-5x01mg | MyBiosource | 5x0.1mg | EUR 5660 |
B7H4 antibody (PE) |
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| MBS834107-100Tests | MyBiosource | 100Tests | EUR 1230 |
B7H4 antibody (PE) |
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| MBS834107-5x100Tests | MyBiosource | 5x100Tests | EUR 5390 |
B7H4 Antibody / VTCN1 |
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| RQ5561 | NSJ Bioreagents | 100 ug | EUR 356.15 |
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Description: V-set domain-containing T-cell activation inhibitor 1 is a protein that in humans is encoded by the VTCN1 gene. It is mapped to 1p13.1-p12. This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. |
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VTCN1 Antibody / B7H4 |
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| V8175-100UG | NSJ Bioreagents | 100 ug | EUR 424.15 |
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Description: T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory proteins. One such protein, B7-H4 (B7-homolog 4), belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells, B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies, including ovarian and breast cancer, as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that, similar to Mucin 16 (CA-125), B7-H4 may be a useful biomarker for the early detection of ovarian cancer. |
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VTCN1 Antibody / B7H4 |
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| V8175-20UG | NSJ Bioreagents | 20 ug | EUR 186.15 |
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Description: T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory proteins. One such protein, B7-H4 (B7-homolog 4), belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells, B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies, including ovarian and breast cancer, as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that, similar to Mucin 16 (CA-125), B7-H4 may be a useful biomarker for the early detection of ovarian cancer. |
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VTCN1 Antibody / B7H4 |
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| V8175SAF-100UG | NSJ Bioreagents | 100 ug | EUR 424.15 |
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Description: T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory proteins. One such protein, B7-H4 (B7-homolog 4), belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells, B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies, including ovarian and breast cancer, as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that, similar to Mucin 16 (CA-125), B7-H4 may be a useful biomarker for the early detection of ovarian cancer. |
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VTCN1 Antibody / B7H4 |
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| V7367-100UG | NSJ Bioreagents | 100 ug | EUR 349.3 |
|
Description: T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory proteins. One such protein, B7-H4 (B7-homolog 4), belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells, B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies, including ovarian and breast cancer, as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that, similar to Mucin 16 (CA-125), B7-H4 may be a useful biomarker for the early detection of ovarian cancer. |
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VTCN1 Antibody / B7H4 |
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| V7367-20UG | NSJ Bioreagents | 20 ug | EUR 153.3 |
|
Description: T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory proteins. One such protein, B7-H4 (B7-homolog 4), belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells, B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies, including ovarian and breast cancer, as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that, similar to Mucin 16 (CA-125), B7-H4 may be a useful biomarker for the early detection of ovarian cancer. |
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VTCN1 Antibody / B7H4 |
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| V7367IHC-7ML | NSJ Bioreagents | 7 ml | EUR 349.3 |
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Description: T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory proteins. One such protein, B7-H4 (B7-homolog 4), belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells, B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies, including ovarian and breast cancer, as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that, similar to Mucin 16 (CA-125), B7-H4 may be a useful biomarker for the early detection of ovarian cancer. |
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VTCN1 Antibody / B7H4 |
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| V7367SAF-100UG | NSJ Bioreagents | 100 ug | EUR 349.3 |
|
Description: T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory proteins. One such protein, B7-H4 (B7-homolog 4), belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells, B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies, including ovarian and breast cancer, as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that, similar to Mucin 16 (CA-125), B7-H4 may be a useful biomarker for the early detection of ovarian cancer. |
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B7H4 antibody (biotin) |
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| 61R-1626 | Fitzgerald | 25 ug | EUR 374 |
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Description: Mouse monoclonal B7H4 antibody (biotin) |
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B7H4 antibody (biotin) |
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| MBS833682-0025mg | MyBiosource | 0.025mg | EUR 650 |
B7H4 antibody (biotin) |
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| MBS833682-5x0025mg | MyBiosource | 5x0.025mg | EUR 2785 |
Human B7H4 ELISA Kit |
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| MBS3804085-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Human B7H4 ELISA Kit |
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| MBS3804085-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Human B7H4 ELISA Kit |
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| MBS3804085-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Human B7H4 ELISA Kit |
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| MBS3804085-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
B7H4 Antibody FITC Conjugated |
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| MBS9459995-01mL | MyBiosource | 0.1mL | EUR 595 |
B7H4 Antibody FITC Conjugated |
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| MBS9459995-5x01mL | MyBiosource | 5x0.1mL | EUR 2525 |
B7H4 Rabbit Monoclonal Antibody |
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| E10G21106 | EnoGene | 100 μl | EUR 275 |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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Mouse Monoclonal Antibody to B7H4 |
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| MBS8537347-01mL | MyBiosource | 0.1mL | EUR 305 |
Mouse Monoclonal Antibody to B7H4 |
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| MBS8537347-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 565 |
Mouse Monoclonal Antibody to B7H4 |
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| MBS8537347-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 565 |
Mouse Monoclonal Antibody to B7H4 |
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| MBS8537347-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 565 |
Mouse Monoclonal Antibody to B7H4 |
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| MBS8537347-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 565 |
Mouse Monoclonal Antibody to B7H4 |
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| MBS8537348-01mL | MyBiosource | 0.1mL | EUR 305 |
Mouse Monoclonal Antibody to B7H4 |
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| MBS8537348-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 565 |
Mouse Monoclonal Antibody to B7H4 |
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| MBS8537348-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 565 |
Mouse Monoclonal Antibody to B7H4 |
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| MBS8537348-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 565 |
Mouse Monoclonal Antibody to B7H4 |
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| MBS8537348-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 565 |
Mouse anti B7H4 Monoclonal Antibody |
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| MBS460837-01mg | MyBiosource | 0.1mg | EUR 320 |
Mouse anti B7H4 Monoclonal Antibody |
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| MBS460837-5x01mg | MyBiosource | 5x0.1mg | EUR 1390 |
Rat Costimulatory molecules B7H4 ELISA kit |
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| E02C0839-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A sandwich ELISA for quantitative measurement of Rat Costimulatory molecules B7H4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Costimulatory molecules B7H4 ELISA kit |
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| E02C0839-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A sandwich ELISA for quantitative measurement of Rat Costimulatory molecules B7H4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Costimulatory molecules B7H4 ELISA kit |
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| E02C0839-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A sandwich ELISA for quantitative measurement of Rat Costimulatory molecules B7H4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Costimulatory molecules B7H4 ELISA kit |
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| E07C0839-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A sandwich ELISA for quantitative measurement of Porcine Costimulatory molecules B7H4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Costimulatory molecules B7H4 ELISA kit |
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| E07C0839-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Porcine Costimulatory molecules B7H4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Costimulatory molecules B7H4 ELISA kit |
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| E07C0839-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Porcine Costimulatory molecules B7H4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog Costimulatory molecules B7H4 ELISA kit |
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| E08C0839-192T | BlueGene | 192 tests | EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Canine Costimulatory molecules B7H4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog Costimulatory molecules B7H4 ELISA kit |
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| E08C0839-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
|
Description: A sandwich ELISA for quantitative measurement of Canine Costimulatory molecules B7H4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog Costimulatory molecules B7H4 ELISA kit |
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| E08C0839-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
|
Description: A sandwich ELISA for quantitative measurement of Canine Costimulatory molecules B7H4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Costimulatory molecules B7H4 ELISA kit |
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| E01A11164 | BlueGene | 96T | EUR 700 |
|
Description: ELISA |
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Cat Costimulatory Molecules B7H4 ELISA Kit |
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| MBS069119-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Rat Costimulatory Molecules B7H4 ELISA Kit |
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| MBS043725-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Rat Costimulatory Molecules B7H4 ELISA Kit |
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| MBS043725-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Rat Costimulatory Molecules B7H4 ELISA Kit |
|||
| MBS043725-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Rat Costimulatory Molecules B7H4 ELISA Kit |
|||
| MBS043725-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Rat Costimulatory molecules B7H4 ELISA Kit |
|||
| MBS751491-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 5685 |
Rat Costimulatory molecules B7H4 ELISA Kit |
|||
| MBS751491-48StripWells | MyBiosource | 48-Strip-Wells | EUR 485 |
Rat Costimulatory molecules B7H4 ELISA Kit |
|||
| MBS751491-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3020 |
Rat Costimulatory molecules B7H4 ELISA Kit |
|||
| MBS751491-96StripWells | MyBiosource | 96-Strip-Wells | EUR 690 |
B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
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| BNC802652-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), CF680 conjugate, Concentration: 0.1mg/mL |
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B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
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| BNC802652-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), CF680 conjugate, Concentration: 0.1mg/mL |
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B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNC812652-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), CF680R conjugate, Concentration: 0.1mg/mL |
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B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNC812652-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), CF680R conjugate, Concentration: 0.1mg/mL |
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B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNC432652-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), CF543 conjugate, Concentration: 0.1mg/mL |
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B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNC432652-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), CF543 conjugate, Concentration: 0.1mg/mL |
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B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNC052652-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), CF405M conjugate, Concentration: 0.1mg/mL |
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B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNC052652-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), CF405M conjugate, Concentration: 0.1mg/mL |
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B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNC552652-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), CF555 conjugate, Concentration: 0.1mg/mL |
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B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNC552652-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), CF555 conjugate, Concentration: 0.1mg/mL |
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B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNC702652-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), CF770 conjugate, Concentration: 0.1mg/mL |
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B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNC702652-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), CF770 conjugate, Concentration: 0.1mg/mL |
|||
B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNC612652-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), CF660R conjugate, Concentration: 0.1mg/mL |
|||
B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNC612652-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), CF660R conjugate, Concentration: 0.1mg/mL |
|||
B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNCH2652-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
|||
B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNCH2652-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
|||
B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNCP2652-250 | Biotium | 250uL | EUR 472.8 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), PerCP conjugate, Concentration: 0.1mg/mL |
|||
B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNCR2652-250 | Biotium | 250uL | EUR 472.8 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), RPE conjugate, Concentration: 0.1mg/mL |
|||
B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNCA2652-250 | Biotium | 250uL | EUR 472.8 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), APC conjugate, Concentration: 0.1mg/mL |
|||
B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNCAP2652-100 | Biotium | 100uL | EUR 279.6 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
|||
B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNCAP2652-500 | Biotium | 500uL | EUR 654 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
|||
B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
|||
| BNUB2652-50 | Biotium | 50uL | EUR 486 |
|
Description: Primary antibody against B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R), 1mg/mL |
|||
Goat Costimulatory molecules B7H4 ELISA kit |
|||
| E01A46077 | BlueGene | 96T | EUR 700 |
|
Description: ELISA |
|||
Goat Costimulatory molecules B7H4 ELISA kit |
|||
| E06C0839-192T | BlueGene | 192 tests | EUR 1524 |
|
Description: A sandwich ELISA for quantitative measurement of Goat Costimulatory molecules B7H4 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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CRISPR/Cas, the immune system of micro organism and archaea.
Microbes depend on various protection mechanisms that permit them to face up to viral predation and publicity to invading nucleic acid. In lots of Micro organism and most Archaea, clustered usually interspaced quick palindromic repeats (CRISPR) type peculiar genetic loci, which give acquired immunity in opposition to viruses and plasmids by concentrating on nucleic acid in a sequence-specific method.
B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
These hypervariable loci take up genetic materials from invasive parts and construct up inheritable DNA-encoded immunity over time. Conversely, viruses have devised mutational escape methods that permit them to bypass the CRISPR/Cas system, albeit at a value.
CRISPR options could also be exploited for typing functions, epidemiological research, host-virus ecological surveys, constructing particular immunity in opposition to undesirable genetic parts, and enhancing viral resistance in domesticated microbes.
Regulation of Adaptive Immunity by the innate immune System
Twenty years after the proposal that sample recognition receptors detect invasion by microbial pathogens, the sphere of immunology has witnessed a number of discoveries which have elucidated receptors and signaling pathways of microbial recognition programs and the way they management the era of T and B lymphocyte-mediated immune responses.
Human vitamin, the intestine microbiome and the Immune System
Nevertheless, there are nonetheless many elementary questions that stay poorly understood, although typically the solutions are assumed to be recognized. Right here, we talk about a few of these questions, together with the mechanisms by which pathogen-specific innate immune recognition prompts antigen-specific adaptive immune responses and the roles of several types of innate immune recognition in host protection from an infection and harm.
Regulatory T cells and mechanisms of immune system management.
The immune system developed to guard the host in opposition to the assault of international, doubtlessly pathogenic, microorganisms. It does so by recognizing antigens expressed by these microorganisms and mounting an immune response in opposition to all cells expressing them, with the final word purpose of their elimination.
Varied mechanisms have been reported to manage and regulate the immune system to forestall or reduce reactivity to self-antigens or an overexuberant response to a pathogen, each of which may end up in harm to the host. Deletion of autoreactive cells throughout T- and B-cell improvement permits the immune system to be tolerant of most self-antigens.
B7-H4 (Immuno-Inhibitory Protein) (B7H4/2652R) Antibody |
Peripheral tolerance to self was advised a number of years in the past to end result from the induction of anergy in peripheral self-reactive lymphocytes. Extra lately, nonetheless, it has develop into clear that avoidance of injury to the host can be achieved by lively suppression mediated by regulatory T (T(reg)) cell populations. We talk about right here the various mechanisms utilized by T(reg) cells to suppress the immune system.
FCRL4 Antibody |
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| DF10173-200ul | Affinity Biosciences | 200ul | EUR 350 |
FCRL4 Antibody |
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| E306620 | EnoGene | 100ug/200ul | EUR 275 |
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Description: Available in various conjugation types. |
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FCRL4 antibody |
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| 70R-7228 | Fitzgerald | 50 ug | EUR 467 |
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Description: Rabbit polyclonal FCRL4 antibody raised against the N terminal of FCRL4 |
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FCRL4 antibody |
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| 70R-7229 | Fitzgerald | 50 ug | EUR 467 |
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Description: Rabbit polyclonal FCRL4 antibody raised against the N terminal of FCRL4 |
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FCRL4 Antibody |
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| ABD10173 | Nova Lifetech | 100ug | EUR 325 |
FCRL4 Antibody |
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| GWB-MR738I | GenWay Biotech | 50ug | Ask for price |
FCRL4 Antibody |
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| GWB-MR739A | GenWay Biotech | 50ug | Ask for price |
FCRL4 Antibody |
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| MBS9401777-01mL | MyBiosource | 0.1mL | EUR 420 |
FCRL4 Antibody |
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| MBS9401777-5x01mL | MyBiosource | 5x0.1mL | EUR 1740 |
FCRL4 Antibody |
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| MBS8513450-005mg | MyBiosource | 0.05mg | EUR 235 |
FCRL4 Antibody |
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| MBS8513450-01mg | MyBiosource | 0.1mg | EUR 305 |
FCRL4 Antibody |
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| MBS8513450-01mLAF405M | MyBiosource | 0.1mL(AF405M) | EUR 465 |
FCRL4 Antibody |
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| MBS8513450-01mLAF546 | MyBiosource | 0.1mL(AF546) | EUR 465 |
FCRL4 Antibody |
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| MBS8513450-01mLAF750 | MyBiosource | 0.1mL(AF750) | EUR 465 |
FCRL4 Antibody |
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| MBS8527017-01mg | MyBiosource | 0.1mg | EUR 345 |
FCRL4 Antibody |
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| MBS8527017-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 565 |
FCRL4 Antibody |
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| MBS8527017-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 565 |
FCRL4 Antibody |
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| MBS8527017-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 565 |
FCRL4 Antibody |
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| MBS8527017-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 565 |
FCRL4 Antibody |
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| MBS1491908-005mg | MyBiosource | 0.05mg | EUR 190 |
FCRL4 Antibody |
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| MBS1491908-01mg | MyBiosource | 0.1mg | EUR 270 |
FCRL4 Antibody |
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| MBS1491908-5x01mg | MyBiosource | 5x0.1mg | EUR 1205 |
FCRL4 Antibody |
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| MBS9603031-01mL | MyBiosource | 0.1mL | EUR 260 |
FCRL4 Antibody |
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| MBS9603031-02mL | MyBiosource | 0.2mL | EUR 305 |
FCRL4 Antibody |
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| MBS9603031-5x02mL | MyBiosource | 5x0.2mL | EUR 1220 |
FCRL4 Antibody |
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| C43766-100ul | Assay Biotech | 100μl | EUR 217 |
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Description: FCRL4 Rabbit Polyclonal Antibody |
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FCRL4 Antibody |
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| C43766-50ul | Assay Biotech | 50μl | EUR 143.5 |
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Description: FCRL4 Rabbit Polyclonal Antibody |
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FCRL4 (untagged)-Human Fc receptor-like 4 (FCRL4) |
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| SC305326 | Origene Technologies GmbH | 10 µg | Ask for price |
FCRL4 (GFP-tagged) - Human Fc receptor-like 4 (FCRL4) |
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| RG216335 | Origene Technologies GmbH | 10 µg | Ask for price |
FCRL4 Rabbit pAb |
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| A10329-100ul | Abclonal | 100 ul | EUR 369.6 |
FCRL4 Rabbit pAb |
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| A10329-200ul | Abclonal | 200 ul | EUR 550.8 |
FCRL4 Rabbit pAb |
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| A10329-20ul | Abclonal | 20 ul | EUR 219.6 |
FCRL4 Rabbit pAb |
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| A10329-50ul | Abclonal | 50 ul | EUR 267.6 |
FCRL4 Rabbit pAb |
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| E2510329 | EnoGene | 100ul | EUR 225 |
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Description: Available in various conjugation types. |
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FCRL4 cDNA Clone |
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| MBS1273596-001mgPlasmid02mLGlycerolStock | MyBiosource | 0.01mgPlasmid+0.2mLGlycerol-Stock | EUR 330 |
FCRL4 cDNA Clone |
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| MBS1273596-5x001mgPlasmid5x02mLGlycerolStock | MyBiosource | 5x0.01mgPlasmid+5x0.2mLGlycerol-Stock | EUR 1430 |
FCRL4 Rabbit pAb |
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| MBS8547854-01mL | MyBiosource | 0.1mL | EUR 305 |
FCRL4 Rabbit pAb |
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| MBS8547854-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 565 |
FCRL4 Rabbit pAb |
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| MBS8547854-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 565 |
FCRL4 Rabbit pAb |
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| MBS8547854-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 565 |
FCRL4 Rabbit pAb |
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| MBS8547854-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 565 |
FCRL4 Rabbit pAb |
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| A10329 | Abclonal | 1000μL | EUR 623.48 |
FCRL4 siRNA (Human) |
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| MBS828888-15nmol | MyBiosource | 15nmol | EUR 405 |
FCRL4 siRNA (Human) |
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| MBS828888-30nmol | MyBiosource | 30nmol | EUR 565 |
FCRL4 siRNA (Human) |
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| MBS828888-5x30nmol | MyBiosource | 5x30nmol | EUR 2450 |
FCRL4 (Myc-DDK-tagged)-Human Fc receptor-like 4 (FCRL4) |
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| RC216335 | Origene Technologies GmbH | 10 µg | Ask for price |
FCRL4 cloning plasmid |
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| CSB-CL836277HU-10ug | Cusabio | 10ug | EUR 451.2 |
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Description: A cloning plasmid for the FCRL4 gene. |
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FCRL4 Blocking Peptide |
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| 33R-2948 | Fitzgerald | 100 ug | EUR 119 |
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Description: A synthetic peptide for use as a blocking control in assays to test for specificity of FCRL4 antibody, catalog no. 70R-7228 |
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FCRL4 Blocking Peptide |
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| 33R-4431 | Fitzgerald | 100 ug | EUR 119 |
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Description: A synthetic peptide for use as a blocking control in assays to test for specificity of FCRL4 antibody, catalog no. 70R-7229 |
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FCRL4 Blocking Peptide |
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| DF10173-BP | Affbiotech | 1mg | EUR 234 |
FCRL4 Blocking Peptide |
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| MBS9620508-1mg | MyBiosource | 1mg | EUR 380 |
FCRL4 Blocking Peptide |
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| MBS9620508-5x1mg | MyBiosource | 5x1mg | EUR 1650 |
FCRL4 Polyclonal Antibody |
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| ABP58542-003ml | Abbkine | 0.03ml | EUR 189.6 |
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Description: A polyclonal antibody for detection of FCRL4 from Human. This FCRL4 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human FCRL4 protein |
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FCRL4 Polyclonal Antibody |
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| ABP58542-01ml | Abbkine | 0.1ml | EUR 346.8 |
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Description: A polyclonal antibody for detection of FCRL4 from Human. This FCRL4 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human FCRL4 protein |
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FCRL4 Polyclonal Antibody |
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| ABP58542-02ml | Abbkine | 0.2ml | EUR 496.8 |
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Description: A polyclonal antibody for detection of FCRL4 from Human. This FCRL4 antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human FCRL4 protein |
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FCRL4 Polyclonal Antibody |
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| 27378 | SAB | 100ul | EUR 439 |
FCRL4 Polyclonal Antibody |
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| 27378-100ul | SAB | 100ul | EUR 302.4 |
FCRL4 Polyclonal Antibody |
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| 27378-50ul | SAB | 50ul | EUR 224.4 |
FCRL4 Polyclonal Antibody |
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| E11-202000 | EnoGene | 100ug/100ul | EUR 225 |
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Description: Available in various conjugation types. |
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FCRL4 Polyclonal Antibody |
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| E910329 | EnoGene | 100ul | EUR 225 |
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Description: Available in various conjugation types. |
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FCRL4 Polyclonal Antibody |
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| A59118 | EpiGentek |
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FCRL4 Polyclonal Antibody |
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| A71988 | EpiGentek | 50 μl | EUR 408 |
FCRL4 Polyclonal Antibody |
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| BT-AP15574-100ul | Jiaxing Korain Biotech Ltd (BT Labs) | 100ul | Ask for price |
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Description: This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. |
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FCRL4 Polyclonal Antibody |
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| BT-AP15574-20ul | Jiaxing Korain Biotech Ltd (BT Labs) | 20ul | Ask for price |
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Description: This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. |
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FCRL4 Polyclonal Antibody |
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| BT-AP15574-50ul | Jiaxing Korain Biotech Ltd (BT Labs) | 50ul | Ask for price |
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Description: This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. |
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FCRL4 Polyclonal Antibody |
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| E44H09607 | EnoGene | 100ul | EUR 255 |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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FCRL4 Polyclonal Antibody |
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| MBS8566428-01mL | MyBiosource | 0.1mL | EUR 305 |
FCRL4 Polyclonal Antibody |
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| MBS8566428-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 565 |
FCRL4 Polyclonal Antibody |
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| MBS8566428-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 565 |
FCRL4 Polyclonal Antibody |
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| MBS8566428-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 565 |
FCRL4 Polyclonal Antibody |
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| MBS8566428-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 565 |
FCRL4 Polyclonal Antibody |
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| MBS9130840-002mL | MyBiosource | 0.02mL | EUR 200 |
FCRL4 Polyclonal Antibody |
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| MBS9130840-005mL | MyBiosource | 0.05mL | EUR 255 |
FCRL4 Polyclonal Antibody |
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| MBS9130840-01mL | MyBiosource | 0.1mL | EUR 345 |
FCRL4 Polyclonal Antibody |
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| MBS9130840-02mL | MyBiosource | 0.2mL | EUR 545 |
FCRL4 Polyclonal Antibody |
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| MBS9130840-5x02mL | MyBiosource | 5x0.2mL | EUR 2265 |
FCRL4 Polyclonal Antibody |
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| MBS8531354-01mg | MyBiosource | 0.1mg | EUR 305 |
FCRL4 Polyclonal Antibody |
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| MBS8531354-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 465 |
FCRL4 Polyclonal Antibody |
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| MBS8531354-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 465 |
FCRL4 Polyclonal Antibody |
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| MBS8531354-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 465 |
FCRL4 Polyclonal Antibody |
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| MBS8531354-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 465 |
FCRL4 Polyclonal Antibody |
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| MBS2547638-006mL | MyBiosource | 0.06mL | EUR 180 |
FCRL4 Polyclonal Antibody |
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| MBS2547638-012mL | MyBiosource | 0.12mL | EUR 260 |
FCRL4 Polyclonal Antibody |
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| MBS2547638-02mL | MyBiosource | 0.2mL | EUR 405 |
FCRL4 Polyclonal Antibody |
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| MBS2547638-5x02mL | MyBiosource | 5x0.2mL | EUR 1725 |
FCRL4 Polyclonal Antibody |
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| MBS9431254-005mL | MyBiosource | 0.05mL | EUR 300 |
FCRL4 Polyclonal Antibody |
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| MBS9431254-01mL | MyBiosource | 0.1mL | EUR 390 |
FCRL4 Polyclonal Antibody |
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| MBS9431254-5x01mL | MyBiosource | 5x0.1mL | EUR 1610 |
FCRL4 Polyclonal Antibody |
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| UB-GEN-6715 | UpingBio | 100 ul | EUR 200 |
FCRL4 Antibody (C-term) |
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| MBS9209999-008mL | MyBiosource | 0.08mL | EUR 210 |
FCRL4 Antibody (C-term) |
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| MBS9209999-04mL | MyBiosource | 0.4mL | EUR 430 |