Th2 cells
th2cells

Suppressor cells as regulators of the immune system.

Posted on by Dominic

 

 

Myeloid-derived suppressor cells as regulators of the immune system.

 

 

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous inhabitants of cells that broaden throughout most cancers, irritation and an infection, and which have a exceptional skill to suppress T-cell responses. These cells represent a singular element of the immune system that regulates immune responses in wholesome people and within the context of varied ailments.
On this Evaluation, we focus on the origin, mechanisms of growth and suppressive features of MDSCs, in addition to the potential to focus on these cells for therapeutic profit.

From irritation to illness and despair: when the immune system subjugates the mind

 

In response to a peripheral an infection, innate immune cells produce pro-inflammatory cytokines that act on the mind to trigger illness behaviour. When activation of the peripheral immune system continues unabated, resembling throughout systemic infections, most cancers or autoimmune ailments, the following immune signalling to the mind can result in an exacerbation of illness and the event of signs of despair in susceptible people.

These phenomena would possibly account for the elevated prevalence of scientific despair in bodily in poor health folks. Irritation is due to this fact an vital organic occasion that may enhance the chance of main depressive episodes, very similar to the extra conventional psychosocial elements.

 

 

 

 

th2cells
th2cells

 

 

Perform and activation of NF-kappa B within the immunesystem.

 

NF-kappa B is a ubiquitous transcription issue. Nonetheless, its properties appear to be most extensively exploited in cells of the immune system. Amongst these properties are NF-kappa B’s fast posttranslational activation in response to many pathogenic alerts, its direct participation in cytoplasmic/nuclear signaling, and its efficiency to activate transcription of a terrific number of genes encoding immunologically related proteins.
In vertebrates, 5 distinct DNA binding subunits are at present identified which could extensively heterodimerize, thereby forming complexes with distinct transcriptional exercise, DNA sequence specificity, and cell type- and cell stage-specific distribution.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Antibody

The exercise of DNA binding NF-kappa B dimers is tightly managed by accent proteins known as I kappa B subunits of which there are additionally 5 completely different species at present identified in vertebrates. I kappa B proteins inhibit DNA binding and stop nuclear uptake of NF-kappa B complexes.

An exception is the Bcl-Three protein which as well as can operate as a transcription activating subunit in th nucleus. Different I kappa B proteins are quite concerned in terminating NF-kappa B’s exercise within the nucleus. The intracellular occasions that result in the inactivation of I kappa B, i.e. the activation of NF-kappa B, are complicated.
They contain phosphorylation and proteolytic reactions and appear to be managed by the cells’ redox standing. Interference with the activation or exercise of NF-kappa B could also be useful in suppressing poisonous/septic shock, graft-vs-host reactions, acute inflammatory reactions, acute part response, and radiation injury.
The inhibition of NF-kappa B activation by antioxidants and particular protease inhibitors might present a pharmacological foundation for interfering with these acute processes.

 

 

 

Rat CMRF35-Like Molecule 1 / IREM1 (CD300LF) ELISA Kit
abx391479-96tests 96 tests
EUR 1093.2

Mouse CMRF35-Like Molecule 1 / IREM1 (CD300LF) ELISA Kit
abx389594-96tests 96 tests
EUR 1093.2

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Antibody
20-abx176897
  • EUR 1378.80
  • EUR 678.00
  • 1 mg
  • 200 ug

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Antibody
20-abx176898
  • EUR 1412.40
  • EUR 693.60
  • 1 mg
  • 200 ug

Recombinant Immune Receptor Expressed On Myeloid Cells 1 (IREM1)
4-RPB377Mu01
  • EUR 539.33
  • EUR 267.60
  • EUR 1692.48
  • EUR 644.16
  • EUR 1168.32
  • EUR 436.80
  • EUR 4051.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Immune Receptor Expressed On Myeloid Cells 1 expressed in: E.coli

Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Protein
20-abx167209
  • EUR 760.80
  • EUR 326.40
  • EUR 2281.20
  • EUR 895.20
  • EUR 543.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Protein
20-abx653796
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
20-abx152058
  • EUR 8534.40
  • EUR 4550.40
  • EUR 1054.80
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
20-abx154266
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) CLIA Kit
20-abx492710
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) CLIA Kit
20-abx492711
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
SEB377Hu-10x96wellstestplate 10x96-wells test plate
EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in Tissue homogenates, cell lysates and other biological fluids.

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
SEB377Hu-1x48wellstestplate 1x48-wells test plate
EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in Tissue homogenates, cell lysates and other biological fluids.

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
SEB377Hu-1x96wellstestplate 1x96-wells test plate
EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in Tissue homogenates, cell lysates and other biological fluids.

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
SEB377Hu-5x96wellstestplate 5x96-wells test plate
EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in Tissue homogenates, cell lysates and other biological fluids.

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
4-SEB377Hu
  • EUR 5463.60
  • EUR 2886.00
  • EUR 735.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
SEB377Mu-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
SEB377Mu-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
SEB377Mu-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
SEB377Mu-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
4-SEB377Mu
  • EUR 5612.40
  • EUR 2965.20
  • EUR 752.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in samples from Tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Mouse Immune Receptor Expressed On Myeloid Cells 1 ELISA Kit (IREM1)
RK02956 96 Tests
EUR 625.2

ELISA kit for Mouse IREM1 (Immune Receptor Expressed On Myeloid Cells 1)
ELK4999 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Immune Receptor Expressed On Myeloid Cells 1 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Human IREM1 (Immune Receptor Expressed On Myeloid Cells 1)
ELK3899 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Immune Receptor Expressed On Myeloid Cells 1 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Polyclonal Antibody (Human, Mouse)
4-PAB377Mu01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1)

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Polyclonal Antibody (Human, Mouse), APC
4-PAB377Mu01-APC
  • EUR 408.00
  • EUR 3843.60
  • EUR 1072.80
  • EUR 518.40
  • EUR 260.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1). This antibody is labeled with APC.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Polyclonal Antibody (Human, Mouse), Biotinylated
4-PAB377Mu01-Biotin
  • EUR 368.40
  • EUR 2888.40
  • EUR 856.80
  • EUR 450.00
  • EUR 260.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1). This antibody is labeled with Biotin.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Polyclonal Antibody (Human, Mouse), Cy3
4-PAB377Mu01-Cy3
  • EUR 493.20
  • EUR 5074.80
  • EUR 1381.20
  • EUR 642.00
  • EUR 297.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1). This antibody is labeled with Cy3.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Polyclonal Antibody (Human, Mouse), FITC
4-PAB377Mu01-FITC
  • EUR 350.40
  • EUR 3098.40
  • EUR 882.00
  • EUR 439.20
  • EUR 232.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1). This antibody is labeled with FITC.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Polyclonal Antibody (Human, Mouse), HRP
4-PAB377Mu01-HRP
  • EUR 373.20
  • EUR 3350.40
  • EUR 949.20
  • EUR 469.20
  • EUR 246.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1). This antibody is labeled with HRP.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Polyclonal Antibody (Human, Mouse), PE
4-PAB377Mu01-PE
  • EUR 350.40
  • EUR 3098.40
  • EUR 882.00
  • EUR 439.20
  • EUR 232.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1). This antibody is labeled with PE.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Polyclonal Antibody (Human, Mouse), APC-Cy7
4-PAB377Mu01-APC-Cy7
  • EUR 672.00
  • EUR 7543.20
  • EUR 2002.80
  • EUR 894.00
  • EUR 378.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1). This antibody is labeled with APC-Cy7.

 

Complement: a key system for immune surveillance and homeostasis.

 

Almost a century after the importance of the human complement system was acknowledged, we have now come to understand that its features prolong far past the elimination of microbes. Complement acts as a fast and environment friendly immune surveillance system that has distinct results on wholesome and altered host cells and overseas intruders.

Recombinant Immune Receptor Expressed On Myeloid Cells 1 (IREM1)
By eliminating mobile particles and infectious microbes, orchestrating immune responses and sending ‘hazard’ alerts, complement contributes considerably to homeostasis, however it could actually additionally take motion towards wholesome cells if not correctly managed.
This overview describes our up to date view of the operate, construction and dynamics of the complement community, highlights its interconnection with immunity at giant and with different endogenous pathways, and illustrates its a number of roles in homeostasis and illness.

Regulation and performance of NF-kappaB transcription elements within the immune system.

 

 

The mammalian Rel/NF-kappaB household of transcription elements, together with RelA, c-Rel, RelB, NF-kappaB1 (p50 and its precursor p105), and NF-kappaB2 (p52 and its precursor p100), performs a central function within the immune system by regulating a number of processes starting from the event and survival of lymphocytes and lymphoid organs to the management of immune responses and malignant transformation.
The 5 members of the NF-kappaB household are usually saved inactive within the cytoplasm by interplay with inhibitors known as IkappaBs or the unprocessed types of NF-kappaB1 and NF-kappaB2. All kinds of alerts emanating from antigen receptors, pattern-recognition receptors, receptors for the members of TNF and IL-1 cytokine households, and others induce differential activation of NF-kappaB heterodimers.

AIRE Polyclonal Antibody
  • Conjugation: Unconjugated
  • Buffer composition: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
  • Purified by: Affinity purification
  • Background: This gene encodes a transcriptional regulator that kinds nuclear our bodies and interacts
Though work over the previous 20 years has shed vital mild on the regulation of NF-kappaB transcription elements and their features, a lot progress has been made up to now two years revealing new insights into the regulation and features of NF-kappaB. This latest progress is roofed on this overview.

 

 

Human Autoimmune Regulator (AIRE) ELISA Kit
RD-AIRE-Hu-48Tests 48 Tests
EUR 625.2

Human Autoimmune Regulator (AIRE) ELISA Kit
RD-AIRE-Hu-96Tests 96 Tests
EUR 867.6

Mouse Autoimmune Regulator (AIRE) ELISA Kit
RD-AIRE-Mu-48Tests 48 Tests
EUR 639.6

Mouse Autoimmune Regulator (AIRE) ELISA Kit
RD-AIRE-Mu-96Tests 96 Tests
EUR 888

Anti-AIRE/Aire 1 Antibody
A00558 100ul
EUR 476.4
Description: Rabbit Polyclonal AIRE/Aire 1 Antibody. Validated in IF, WB and tested in Human, Mouse.

AIRE Antibody
1-CSB-PA001502HA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

AIRE Antibody
CSB-PA001502KA01HU-100ul 100ul
EUR 466.8
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

AIRE Antibody
CSB-PA274868-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

AIRE Antibody
1-CSB-PA000839
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IF, ELISA;WB:1/500-1/2000.IF:1/200-1/1000.ELISA:1/10000

AIRE Antibody
1-CSB-PA009261
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000

AIRE Antibody
DF3026 200ul
EUR 420

AIRE Antibody
DF6603 200ul
EUR 420

AIRE Antibody
AF6841 100ul
EUR 420

AIRE Antibody
AF0334 200ul
EUR 420

AIRE antibody
70R-34455 100 ug
EUR 392.4
Description: Rabbit polyclonal AIRE antibody

AIRE antibody
70R-33714 100 ug
EUR 392.4
Description: Rabbit polyclonal AIRE antibody

AIRE antibody
70R-51449 100 ul
EUR 292.8
Description: Purified Polyclonal AIRE antibody

AIRE Antibody
32424-100ul 100ul
EUR 302.4

AIRE Peptide
45-225P 0.1 mg
EUR 405.6
Description: (CT) AIRE Peptide

AIRE Peptide
45-226P 0.1 mg
EUR 405.6
Description: (IN) AIRE Peptide

AIRE Peptide
45-227P 0.1 mg
EUR 405.6
Description: (IN) AIRE Peptide

AIRE Antibody
33590-100ul 100ul
EUR 302.4

AIRE Antibody
33590-50ul 50ul
EUR 224.4

AIRE Antibody
ABD3026 100 ug
EUR 525.6

AIRE Antibody
ABF0334 100 ug
EUR 525.6

AIRE Antibody
ABF5471 100 ug
EUR 525.6

AIRE Antibody
ABD6603 100 ug
EUR 525.6

AIRE siRNA
20-abx907108
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

AIRE siRNA
20-abx907109
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

AIRE Antibody
R32465 100 ug
EUR 419

AIRE Antibody
R34350-100UG 100 ug
EUR 399

AIRE Antibody
R34389-100UG 100 ug
EUR 399

AIRE Antibody
R35463-100UG 100 ug
EUR 399

AIRE Antibody
CSB-PA001502KA01HU- each
EUR 402
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

AIRE Antibody
CSB-PA274868- each
EUR 402
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

AIRE Blocking Peptide
DF3026-BP 1mg
EUR 234

AIRE Blocking Peptide
DF6603-BP 1mg
EUR 234

AIRE Conjugated Antibody
C32424 100ul
EUR 476.4

AIRE Blocking Peptide
AF0334-BP 1mg
EUR 234

anti- AIRE antibody
FNab00241 100µg
EUR 606.3
Description: Antibody raised against AIRE

AIRE antibody (Ser156)
70R-34454 100 ug
EUR 392.4
Description: Rabbit polyclonal AIRE antibody (Ser156)

AIRE Rabbit pAb
A14183-100ul 100 ul
EUR 369.6

AIRE Rabbit pAb
A14183-200ul 200 ul
EUR 550.8

AIRE Rabbit pAb
A14183-20ul 20 ul
EUR 219.6

AIRE Rabbit pAb
A14183-50ul 50 ul
EUR 267.6

AIRE Blocking Peptide
20-abx062024
  • EUR 326.40
  • EUR 493.20
  • 1 mg
  • 5 mg

AIRE Rabbit pAb
A1767-100ul 100 ul
EUR 369.6

AIRE Rabbit pAb
A1767-200ul 200 ul
EUR 550.8

AIRE Rabbit pAb
A1767-20ul 20 ul
EUR 219.6

AIRE Rabbit pAb
A1767-50ul 50 ul
EUR 267.6

AIRE (pS156) Antibody
abx332932-100ul 100 ul
EUR 560.4

Polyclonal AIRE Antibody
APR03336G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human AIRE . This antibody is tested and proven to work in the following applications:

AIRE (isoform 1)
GT41000 100 ug
EUR 568.8

Anti-AIRE Antibody
PB9980 100ug/vial
EUR 400.8

Anti-AIRE antibody
PAab00241 100 ug
EUR 426

Anti-AIRE antibody
STJ70203 100 µg
EUR 430.8

Anti-AIRE antibody
STJ70934 100 µg
EUR 430.8

Anti-AIRE antibody
STJ71077 100 µg
EUR 430.8

Anti-AIRE antibody
STJ22559 100 µl
EUR 332.4
Description: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

Anti-AIRE antibody
STJ116116 100 µl
EUR 332.4
Description: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

Phospho-AIRE (Ser156) Antibody
CSB-PA217298-100ul 100ul
EUR 434.4
Description: A polyclonal antibody against Phospho-AIRE (Ser156). Recognizes Phospho-AIRE (Ser156) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

AIRE Antibody, HRP conjugated
1-CSB-PA001502HB01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

AIRE Antibody, FITC conjugated
1-CSB-PA001502HC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

AIRE Antibody, Biotin conjugated
1-CSB-PA001502HD01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

AIRE-1 Polyclonal Antibody
ABP50619-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of AIRE-1 from Human, Mouse. This AIRE-1 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140

AIRE-1 Polyclonal Antibody
ABP50619-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of AIRE-1 from Human, Mouse. This AIRE-1 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140

AIRE-1 Polyclonal Antibody
ABP50619-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of AIRE-1 from Human, Mouse. This AIRE-1 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140

Phospho-AIRE (S156) Antibody
1-CSB-PA009259
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Phospho-AIRE (S156). Recognizes Phospho-AIRE (S156) from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000

Phospho-AIRE (Ser156) Antibody
AF3841 100ul
EUR 540

Human AIRE shRNA Plasmid
20-abx950227
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse AIRE shRNA Plasmid
20-abx969093
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse AIRE ELISA Kit
EMA0534 96Tests
EUR 625.2

Monkey AIRE ELISA Kit
EMKA0534 96Tests
EUR 625.2

Sheep AIRE ELISA Kit
ESA0534 96Tests
EUR 625.2

AIRE-1 Polyclonal Antibody
ES1618-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

AIRE-1 Polyclonal Antibody
ES1618-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

AIRE-1 Polyclonal Antibody
ES5772-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

AIRE-1 Polyclonal Antibody
ES5772-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Human AIRE ELISA Kit
EHA0534 96Tests
EUR 625.2

Rat AIRE ELISA Kit
ERA0534 96Tests
EUR 625.2

Porcine AIRE ELISA Kit
EPA0534 96Tests
EUR 625.2

Rabbit AIRE ELISA Kit
ERTA0534 96Tests
EUR 625.2

Autoimmune regulator (AIRE) Antibody
48129-100ul 100ul
EUR 399.6

Autoimmune regulator (AIRE) Antibody
48129-50ul 50ul
EUR 286.8

Autoimmune regulator (AIRE) Antibody
48149-100ul 100ul
EUR 399.6

Autoimmune regulator (AIRE) Antibody
48149-50ul 50ul
EUR 286.8

AIRE-1 Polyclonal Antibody
40562-100ul 100ul
EUR 302.4

AIRE-1 Polyclonal Antibody
40562-50ul 50ul
EUR 224.4

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