th2cells

Suppressor cells as regulators of the immune system.

Posted on by Dominic

 

 

Myeloid-derived suppressor cells as regulators of the immune system.

 

 

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous inhabitants of cells that broaden throughout most cancers, irritation and an infection, and which have a exceptional skill to suppress T-cell responses. These cells represent a singular element of the immune system that regulates immune responses in wholesome people and within the context of varied ailments.
On this Evaluation, we focus on the origin, mechanisms of growth and suppressive features of MDSCs, in addition to the potential to focus on these cells for therapeutic profit.

From irritation to illness and despair: when the immune system subjugates the mind

 

In response to a peripheral an infection, innate immune cells produce pro-inflammatory cytokines that act on the mind to trigger illness behaviour. When activation of the peripheral immune system continues unabated, resembling throughout systemic infections, most cancers or autoimmune ailments, the following immune signalling to the mind can result in an exacerbation of illness and the event of signs of despair in susceptible people.

These phenomena would possibly account for the elevated prevalence of scientific despair in bodily in poor health folks. Irritation is due to this fact an vital organic occasion that may enhance the chance of main depressive episodes, very similar to the extra conventional psychosocial elements.

 

 

 

 

th2cells
th2cells

 

 

Perform and activation of NF-kappa B within the immunesystem.

 

NF-kappa B is a ubiquitous transcription issue. Nonetheless, its properties appear to be most extensively exploited in cells of the immune system. Amongst these properties are NF-kappa B’s fast posttranslational activation in response to many pathogenic alerts, its direct participation in cytoplasmic/nuclear signaling, and its efficiency to activate transcription of a terrific number of genes encoding immunologically related proteins.
In vertebrates, 5 distinct DNA binding subunits are at present identified which could extensively heterodimerize, thereby forming complexes with distinct transcriptional exercise, DNA sequence specificity, and cell type- and cell stage-specific distribution.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Antibody

The exercise of DNA binding NF-kappa B dimers is tightly managed by accent proteins known as I kappa B subunits of which there are additionally 5 completely different species at present identified in vertebrates. I kappa B proteins inhibit DNA binding and stop nuclear uptake of NF-kappa B complexes.

An exception is the Bcl-Three protein which as well as can operate as a transcription activating subunit in th nucleus. Different I kappa B proteins are quite concerned in terminating NF-kappa B’s exercise within the nucleus. The intracellular occasions that result in the inactivation of I kappa B, i.e. the activation of NF-kappa B, are complicated.
They contain phosphorylation and proteolytic reactions and appear to be managed by the cells’ redox standing. Interference with the activation or exercise of NF-kappa B could also be useful in suppressing poisonous/septic shock, graft-vs-host reactions, acute inflammatory reactions, acute part response, and radiation injury.
The inhibition of NF-kappa B activation by antioxidants and particular protease inhibitors might present a pharmacological foundation for interfering with these acute processes.

 

 

 

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
RD-IREM1-Hu-96Tests 96 Tests
EUR 692

IREM1 ELISA Kit (Human) (OKDD00344)
OKDD00344 96 Wells
EUR 923
Description: Description of target: This gene encodes a member of the CD300 protein family. Members of this family are cell surface glycoproteins with a single IgV-like extracellular domain, and are involved in the regulation of immune response. The encoded protein is an inhibitory receptor. Alternative splicing results in multiple transcript variants.;Species reactivity: Human;Application: ;Assay info: Quantitative Sandwich ELISA;Sensitivity: < 0.062 ng/mL

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Antibody
20-abx176897
  • EUR 1149.00
  • EUR 565.00
  • 1 mg
  • 200 ug
  • Please enquire.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Antibody
20-abx176898
  • EUR 1177.00
  • EUR 578.00
  • 1 mg
  • 200 ug
  • Please enquire.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Antibody
20-abx129553
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Antibody
20-abx172864
  • EUR 815.00
  • EUR 425.00
  • 1 mg
  • 200 ug
  • Please enquire.

Rat CMRF35-Like Molecule 1 / IREM1 (CD300LF) ELISA Kit
abx391479-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

Human CMRF35-Like Molecule 1 / IREM1 (CD300LF) ELISA Kit
abx386392-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

Mouse CMRF35-Like Molecule 1 / IREM1 (CD300LF) ELISA Kit
abx389594-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

Recombinant Immune Receptor Expressed On Myeloid Cells 1 (IREM1)
4-RPB377Mu01
  • EUR 449.44
  • EUR 223.00
  • EUR 1410.40
  • EUR 536.80
  • EUR 973.60
  • EUR 364.00
  • EUR 3376.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q6SJQ7
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 58.9kDa
  • Isoelectric Point: 6.1
Description: Recombinant Mouse Immune Receptor Expressed On Myeloid Cells 1 expressed in: E.coli

Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Protein
20-abx167209
  • EUR 634.00
  • EUR 272.00
  • EUR 1901.00
  • EUR 746.00
  • EUR 453.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Protein
20-abx653796
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
20-abx154266
  • EUR 7237.00
  • EUR 3855.00
  • EUR 895.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
20-abx152058
  • EUR 7112.00
  • EUR 3792.00
  • EUR 879.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) CLIA Kit
20-abx492710
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) CLIA Kit
20-abx492711
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
SEB377Hu-10x96wellstestplate 10x96-wells test plate
EUR 4502.43
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<1
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in Tissue homogenates, cell lysates and other biological fluids.

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
SEB377Hu-1x48wellstestplate 1x48-wells test plate
EUR 458.44
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<1
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in Tissue homogenates, cell lysates and other biological fluids.

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
SEB377Hu-1x96wellstestplate 1x96-wells test plate
EUR 612.05
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<1
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in Tissue homogenates, cell lysates and other biological fluids.

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
SEB377Hu-5x96wellstestplate 5x96-wells test plate
EUR 2454.23
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<1
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in Tissue homogenates, cell lysates and other biological fluids.

Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
4-SEB377Hu
  • EUR 4553.00
  • EUR 2405.00
  • EUR 613.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Immune Receptor Expressed On Myeloid Cells 1 elisa. Alternative names of the recognized antigen: CD300f
  • CD300LF
  • NKIR
  • IGSF13
  • CLM1
  • CD300 Antigen Like Family Member F
  • CMRF35-Like Molecule 1
  • Immunoglobulin superfamily member 13
  • NK i
  • Show more
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
SEB377Mu-10x96wellstestplate 10x96-wells test plate
EUR 4626.78
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<1
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
SEB377Mu-1x48wellstestplate 1x48-wells test plate
EUR 468.68
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<1
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
SEB377Mu-1x96wellstestplate 1x96-wells test plate
EUR 626.68
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<1
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
SEB377Mu-5x96wellstestplate 5x96-wells test plate
EUR 2520.06
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<1
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) ELISA Kit
4-SEB377Mu
  • EUR 4677.00
  • EUR 2471.00
  • EUR 627.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Immune Receptor Expressed On Myeloid Cells 1 elisa. Alternative names of the recognized antigen: CD300f
  • CD300LF
  • NKIR
  • IGSF13
  • CLM1
  • CD300 Antigen Like Family Member F
  • CMRF35-Like Molecule 1
  • Immunoglobulin superfamily member 13
  • NK i
  • Show more
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1) in samples from Tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Mouse Immune Receptor Expressed On Myeloid Cells 1 ELISA Kit (IREM1)
RK02956 96 Tests
EUR 521

ELISA kit for Human IREM1 (Immune Receptor Expressed On Myeloid Cells 1)
ELK3899 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Immune Receptor Expressed On Myeloid Cells 1 (IREM1). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated an
  • Show more
Description: A sandwich ELISA kit for detection of Immune Receptor Expressed On Myeloid Cells 1 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Mouse IREM1 (Immune Receptor Expressed On Myeloid Cells 1)
ELK4999 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Immune Receptor Expressed On Myeloid Cells 1 (IREM1). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated an
  • Show more
Description: A sandwich ELISA kit for detection of Immune Receptor Expressed On Myeloid Cells 1 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Polyclonal Antibody (Human, Mouse)
4-PAB377Mu01
  • EUR 243.00
  • EUR 2457.00
  • EUR 613.00
  • EUR 305.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IREM1 (Ser45~Ile310)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1)

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Polyclonal Antibody (Human, Mouse), APC
4-PAB377Mu01-APC
  • EUR 340.00
  • EUR 3203.00
  • EUR 894.00
  • EUR 432.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IREM1 (Ser45~Ile310)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1). This antibody is labeled with APC.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Polyclonal Antibody (Human, Mouse), Biotinylated
4-PAB377Mu01-Biotin
  • EUR 307.00
  • EUR 2407.00
  • EUR 714.00
  • EUR 375.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IREM1 (Ser45~Ile310)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1). This antibody is labeled with Biotin.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Polyclonal Antibody (Human, Mouse), Cy3
4-PAB377Mu01-Cy3
  • EUR 411.00
  • EUR 4229.00
  • EUR 1151.00
  • EUR 535.00
  • EUR 248.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IREM1 (Ser45~Ile310)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1). This antibody is labeled with Cy3.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Polyclonal Antibody (Human, Mouse), FITC
4-PAB377Mu01-FITC
  • EUR 292.00
  • EUR 2582.00
  • EUR 735.00
  • EUR 366.00
  • EUR 194.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IREM1 (Ser45~Ile310)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1). This antibody is labeled with FITC.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Polyclonal Antibody (Human, Mouse), HRP
4-PAB377Mu01-HRP
  • EUR 311.00
  • EUR 2792.00
  • EUR 791.00
  • EUR 391.00
  • EUR 205.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IREM1 (Ser45~Ile310)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1). This antibody is labeled with HRP.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Polyclonal Antibody (Human, Mouse), PE
4-PAB377Mu01-PE
  • EUR 292.00
  • EUR 2582.00
  • EUR 735.00
  • EUR 366.00
  • EUR 194.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IREM1 (Ser45~Ile310)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1). This antibody is labeled with PE.

Immune Receptor Expressed On Myeloid Cells 1 (IREM1) Polyclonal Antibody (Human, Mouse), APC-Cy7
4-PAB377Mu01-APC-Cy7
  • EUR 560.00
  • EUR 6286.00
  • EUR 1669.00
  • EUR 745.00
  • EUR 315.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: IREM1 (Ser45~Ile310)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse Immune Receptor Expressed On Myeloid Cells 1 (IREM1). This antibody is labeled with APC-Cy7.

 

Complement: a key system for immune surveillance and homeostasis.

 

Almost a century after the importance of the human complement system was acknowledged, we have now come to understand that its features prolong far past the elimination of microbes. Complement acts as a fast and environment friendly immune surveillance system that has distinct results on wholesome and altered host cells and overseas intruders.

Recombinant Immune Receptor Expressed On Myeloid Cells 1 (IREM1)
By eliminating mobile particles and infectious microbes, orchestrating immune responses and sending ‘hazard’ alerts, complement contributes considerably to homeostasis, however it could actually additionally take motion towards wholesome cells if not correctly managed.
This overview describes our up to date view of the operate, construction and dynamics of the complement community, highlights its interconnection with immunity at giant and with different endogenous pathways, and illustrates its a number of roles in homeostasis and illness.

Regulation and performance of NF-kappaB transcription elements within the immune system.

 

 

The mammalian Rel/NF-kappaB household of transcription elements, together with RelA, c-Rel, RelB, NF-kappaB1 (p50 and its precursor p105), and NF-kappaB2 (p52 and its precursor p100), performs a central function within the immune system by regulating a number of processes starting from the event and survival of lymphocytes and lymphoid organs to the management of immune responses and malignant transformation.
The 5 members of the NF-kappaB household are usually saved inactive within the cytoplasm by interplay with inhibitors known as IkappaBs or the unprocessed types of NF-kappaB1 and NF-kappaB2. All kinds of alerts emanating from antigen receptors, pattern-recognition receptors, receptors for the members of TNF and IL-1 cytokine households, and others induce differential activation of NF-kappaB heterodimers.

AIRE Polyclonal Antibody
  • Conjugation: Unconjugated
  • Buffer composition: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
  • Purified by: Affinity purification
  • Background: This gene encodes a transcriptional regulator that kinds nuclear our bodies and interacts
Though work over the previous 20 years has shed vital mild on the regulation of NF-kappaB transcription elements and their features, a lot progress has been made up to now two years revealing new insights into the regulation and features of NF-kappaB. This latest progress is roofed on this overview.

 

 

Human Autoimmune Regulator (AIRE) ELISA Kit
RD-AIRE-Hu-48Tests 48 Tests
EUR 521

Human Autoimmune Regulator (AIRE) ELISA Kit
RD-AIRE-Hu-96Tests 96 Tests
EUR 723

Mouse Autoimmune Regulator (AIRE) ELISA Kit
RD-AIRE-Mu-48Tests 48 Tests
EUR 533

Mouse Autoimmune Regulator (AIRE) ELISA Kit
RD-AIRE-Mu-96Tests 96 Tests
EUR 740

Human Autoimmune Regulator (AIRE) ELISA Kit
RDR-AIRE-Hu-48Tests 48 Tests
EUR 544

Human Autoimmune Regulator (AIRE) ELISA Kit
RDR-AIRE-Hu-96Tests 96 Tests
EUR 756

Mouse Autoimmune Regulator (AIRE) ELISA Kit
RDR-AIRE-Mu-48Tests 48 Tests
EUR 557

Mouse Autoimmune Regulator (AIRE) ELISA Kit
RDR-AIRE-Mu-96Tests 96 Tests
EUR 774

Anti-AIRE/Aire 1 Antibody
A00558 100ul
EUR 397
Description: Rabbit Polyclonal AIRE/Aire 1 Antibody. Validated in IF, WB and tested in Human, Mouse.

AIRE siRNA
20-abx907108
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol
  • Shipped within 5-10 working days.

AIRE siRNA
20-abx907109
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol
  • Shipped within 5-10 working days.

AIRE Antibody
AF0334 200ul
EUR 304
Description: AIRE antibody detects endogenous levels of total AIRE.

AIRE Antibody
ABF5471 100 ug
EUR 438

AIRE Antibody
ABF0334 100 ug
EUR 438

AIRE antibody
70R-51449 100 ul
EUR 244
Description: Purified Polyclonal AIRE antibody

AIRE antibody
70R-33714 100 ug
EUR 327
Description: Rabbit polyclonal AIRE antibody

AIRE antibody
70R-34455 100 ug
EUR 327
Description: Rabbit polyclonal AIRE antibody

AIRE Antibody
ABD3026 100 ug
EUR 438

AIRE Antibody
ABD6603 100 ug
EUR 438

AIRE Antibody
33590-100ul 100ul
EUR 252

AIRE Antibody
33590-50ul 50ul
EUR 187

AIRE Antibody
32424-100ul 100ul
EUR 252

AIRE Antibody
DF6603 200ul
EUR 304
Description: AIRE Antibody detects endogenous levels of total AIRE.

AIRE Antibody
DF3026 200ul
EUR 304
Description: AIRE Antibody detects endogenous levels of total AIRE.

AIRE Antibody
1-CSB-PA000839
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IF, ELISA;WB:1/500-1/2000.IF:1/200-1/1000.ELISA:1/10000

AIRE Antibody
1-CSB-PA001502HA01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

AIRE Antibody
CSB-PA001502KA01HU-
EUR 335
  • Form: liquid
  • Buffer: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Affinity purification
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

AIRE Antibody
CSB-PA001502KA01HU-100ul 100ul
EUR 389
  • Form: liquid
  • Buffer: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Affinity purification
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

AIRE Antibody
CSB-PA274868-
EUR 335
  • Form: liquid
  • Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific
  • Show more
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

AIRE Antibody
CSB-PA274868-100ul 100ul
EUR 316
  • Form: liquid
  • Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific
  • Show more
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

AIRE Antibody
1-CSB-PA009261
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000

Polyclonal AIRE Antibody
APR03336G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human AIRE . This antibody is tested and proven to work in the following applications:

AIRE Conjugated Antibody
C32424 100ul
EUR 397

AIRE Blocking Peptide
AF0334-BP 1mg
EUR 195

AIRE (isoform 1)
GT41000 100 ug
EUR 474

anti- AIRE antibody
FNab00241 100µg
EUR 505.25
  • Recommended dilution: WB: 1:500-1:5000
  • IHC: 1:20-200
  • Immunogen: autoimmune regulator
  • Uniprot ID: O43918
  • Gene ID: 326
  • Research Area: Metabolism
Description: Antibody raised against AIRE

AIRE Blocking Peptide
20-abx062024
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg
  • Shipped within 5-10 working days.

AIRE (pS156) Antibody
abx332932-100ul 100 ul
EUR 467
  • Shipped within 5-10 working days.

AIRE antibody (Ser156)
70R-34454 100 ug
EUR 327
Description: Rabbit polyclonal AIRE antibody (Ser156)

AIRE Rabbit pAb
A1767-100ul 100 ul
EUR 308

AIRE Rabbit pAb
A1767-200ul 200 ul
EUR 459

AIRE Rabbit pAb
A1767-20ul 20 ul
EUR 183

AIRE Rabbit pAb
A1767-50ul 50 ul
EUR 223

AIRE Rabbit pAb
A14183-100ul 100 ul
EUR 308

AIRE Rabbit pAb
A14183-200ul 200 ul
EUR 459

AIRE Rabbit pAb
A14183-20ul 20 ul
EUR 183

AIRE Rabbit pAb
A14183-50ul 50 ul
EUR 223

AIRE Blocking Peptide
DF6603-BP 1mg
EUR 195

AIRE Blocking Peptide
DF3026-BP 1mg
EUR 195

Anti-AIRE Antibody
PB9980 100ug/vial
EUR 334

Anti-AIRE antibody
PAab00241 100 ug
EUR 355

Anti-AIRE antibody
STJ70203 100 µg
EUR 359

Anti-AIRE antibody
STJ70934 100 µg
EUR 359

Anti-AIRE antibody
STJ71077 100 µg
EUR 359

Anti-AIRE antibody
STJ22559 100 µl
EUR 277
Description: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

Anti-AIRE antibody
STJ116116 100 µl
EUR 277
Description: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

Polyclonal AIRE Antibody (Internal)
APG00998G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human AIRE (Internal). This antibody is tested and proven to work in the following applications:

AIRE Cell ELISA Kit
abx595022-96tests 96 tests
EUR 637
  • Shipped within 1-2 weeks.

Human AIRE ELISA Kit
EHA0534 96Tests
EUR 521

Human AIRE ELISA Kit
ELA-E13302h 96 Tests
EUR 824

Goat AIRE ELISA Kit
EGTA0534 96Tests
EUR 521

Canine AIRE ELISA Kit
ECA0534 96Tests
EUR 521

Chicken AIRE ELISA Kit
ECKA0534 96Tests
EUR 521

Bovine AIRE ELISA Kit
EBA0534 96Tests
EUR 521

Anserini AIRE ELISA Kit
EAA0534 96Tests
EUR 521

AIRE ELISA KIT|Human
EF005361 96 Tests
EUR 689

AIRE-1 Polyclonal Antibody
ES1618-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

AIRE-1 Polyclonal Antibody
ES1618-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

AIRE-1 Polyclonal Antibody
ES5772-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

AIRE-1 Polyclonal Antibody
ES5772-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Rat AIRE ELISA Kit
ERA0534 96Tests
EUR 521

Rabbit AIRE ELISA Kit
ERTA0534 96Tests
EUR 521

Sheep AIRE ELISA Kit
ESA0534 96Tests
EUR 521

Porcine AIRE ELISA Kit
EPA0534 96Tests
EUR 521

Mouse AIRE ELISA Kit
EMA0534 96Tests
EUR 521

Monkey AIRE ELISA Kit
EMKA0534 96Tests
EUR 521

Autoimmune Regulator (AIRE) Antibody
abx117155-100ug 100 ug
EUR 467
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody
20-abx001466
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody
abx038141-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

AIRE-1 Polyclonal Antibody
ABP50619-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human, Mouse. This AIRE-1 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140

AIRE-1 Polyclonal Antibody
ABP50619-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human, Mouse. This AIRE-1 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140

AIRE-1 Polyclonal Antibody
ABP50619-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human, Mouse. This AIRE-1 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140

Autoimmune Regulator (AIRE) Antibody
20-abx013298
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody
20-abx007582
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody
abx019018-100ug 100 ug
EUR 342
  • Shipped within 5-10 working days.

AIRE-1 Polyclonal Antibody
ABP54773-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human. This AIRE-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156

AIRE-1 Polyclonal Antibody
ABP54773-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human. This AIRE-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156

AIRE-1 Polyclonal Antibody
ABP54773-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human. This AIRE-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156

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