A platinum(II) phenylphenanthroimidazole with an prolonged side-chain reveals sluggish dissociation from a c-Equipment G-quadruplex motif. A collection of three platinum(II) phenanthroimidazoles every containing a protonable side-chain appended from the phenyl moiety by way of copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) have been evaluated for his or her capacities to bind to human telomere, c-Myc, and c-Equipment derived G-quadruplexes….
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